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Research Article | Volume 25 Issue 1 (, 2019) | Pages 1 - 7
Advances in Stem Cell Therapy for Heart Valve Regeneration
Cioffi G.
 ,
Mazzone C.
 ,
Barbati G.
 ,
Rossi A.
 ,
Nistri S.
 ,
Ognibeni F.
 ,
Tarantini L.
 ,
Di Lenarda A.
 ,
Faggiano P.
 ,
Pulignano G.
 ,
Stefenelli C.
 ,
de Simone G.
Under a Creative Commons license
Open Access
Received
Feb. 3, 2019
Revised
April 15, 2019
Accepted
Oct. 5, 2019
Published
Dec. 30, 2019
Abstract

Stem cell therapy offers promising potential for heart valve regeneration, presenting an innovative approach to addressing valve-related pathologies and limitations of current prosthetic and bioprosthetic valves. This review explores the recent advancements in stem cell-based strategies for heart valve regeneration, including various stem cell sources, tissue engineering techniques, and preclinical and clinical outcomes. We highlight the challenges and future directions in this rapidly evolving field.

Keywords
Stem cell therapy
Heart valve regeneration
Tissue engineering
Stem cell sources
Regenerative medicine
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Journal of Heart Valve Disease
Open Access
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