Biomechanics of Heart Valves: From Normal Function to Disease States

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Research Article | Volume 24 Issue 1 (, 2018) | Pages 1 - 7

Biomechanics of Heart Valves: From Normal Function to Disease States

Rudzinski P.N.

Dzielinska Z.

Witkowski A.

Konka M.

Katarzyna K.-L.

Demkow M.

Under a Creative Commons license

Open Access

Received

Jan. 13, 2018

Revised

May 27, 2018

Accepted

Oct. 7, 2018

Published

Dec. 30, 2018

Abstract

The biomechanics of heart valves play a crucial role in their normal function and in the development of valvular heart diseases. This review explores the mechanical principles underlying normal heart valve function, the changes that occur in disease states, and how these alterations contribute to clinical manifestations of valve dysfunction. We discuss the impact of mechanical stress, strain, and fatigue on valve tissues, and highlight advances in imaging and computational modeling that have enhanced our understanding of valve biomechanics. The implications for diagnosis and treatment are also examined, with a focus on emerging technologies and therapeutic strategies.

Keywords

Heart valve biomechanics

Normal function

Disease states

Mechanical stress

Computational modeling

Imaging techniques

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