Exploring the Role of MicroRNAs in Heart Valve Development and Disease

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Research Article | Volume 28 Issue 1 (, 2023) | Pages 1 - 5

Exploring the Role of MicroRNAs in Heart Valve Development and Disease

Ruparelia N.

Panoulas V.F.

Frame A.

Sutaria N.

Ariff B.

Gopalan D.

Chukwuemeka A.

Mikhail G.W.

Malik I.S.

Under a Creative Commons license

Open Access

Received

Feb. 4, 2022

Revised

June 15, 2022

Accepted

Oct. 12, 2022

Published

Dec. 30, 2022

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs that play critical roles in the regulation of gene expression. In the context of heart valve development and disease, miRNAs have emerged as important regulators of cellular processes, including differentiation, proliferation, and apoptosis. This review explores the roles of various miRNAs in heart valve development and pathology, examining their mechanisms of action, potential as diagnostic biomarkers, and therapeutic targets. We summarize recent findings and discuss future directions for research in this evolving field.

Keywords

MicroRNAs

Heart valve development

Heart valve disease

Gene regulation

Biomarkers

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