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Research Article | Volume 27 Issue 1 (, 2022) | Pages 1 - 6
Novel Drug Therapies for Inhibiting Heart Valve Calcification
Gopalakrishnan A.
 ,
Kumar Mohanan Nair K.
 ,
Harikrishnan S.
 ,
Valaparambil A.
Under a Creative Commons license
Open Access
Received
Jan. 13, 2021
Revised
May 20, 2021
Accepted
Sept. 25, 2021
Published
Dec. 30, 2021
Abstract

Heart valve calcification is a significant contributor to the progression of aortic stenosis and other valvular heart diseases. This article reviews the latest advancements in novel drug therapies aimed at inhibiting heart valve calcification. We discuss the mechanisms through which these drugs act, their efficacy in preclinical and clinical trials, and the potential for future therapeutic developments.

Keywords
Heart valve calcification
Drug therapies
Aortic stenosis
Calcification inhibitors
Therapeutic advancements
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Journal of Heart Valve Disease
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