Contents
Download PDF
pdf Download XML
7 Views
1 Downloads
Share this article
Research Article | Volume 30 Issue 7 (July, 2025) | Pages 270 - 273
To Evaluate and Correlate the Role of Ultrasonography with Fine Needle Aspiration Cytology in Patient of Thyroid Lesions
 ,
 ,
 ,
 ,
1
PG Resident 3rd Year, Dept. of Radio diagnosis, Amaltas Institute of Medical Sciences, Dewas, M.P.
2
Professor & H.O.D, Dept. of Radio diagnosis, Amaltas Institute of Medical Sciences, Dewas, M.P.
3
Assistant Professor, Dept. of Radio diagnosis, Amaltas Institute of Medical Sciences, Dewas, M.P.
Under a Creative Commons license
Open Access
Received
June 10, 2025
Revised
July 15, 2025
Accepted
July 25, 2025
Published
July 31, 2025
Abstract

Background & Methods: The aim of the study is to evaluate and correlate the role of ultrasonography with fine needle aspiration cytology in patient of thyroid lesions. The study was performed in the Department of Radio-diagnosis, Amaltas Institute of Medical Sciences Aims Dewas to evaluate the sonographic findings of thyroid lesions with FNAC fine needle aspiration cytology correlation in the diagnosis of Thyroid disorder. Results: Out of 44 patients, 34.09% had < 5 mm nodule size, 15.91% had 5mm -1 cm5mm -1 cm and 50% had  >1 cm nodule size. 44% had Homogeneous whereas 56% had Heterogeenous type of echotexture of thyroid parenchyma. Out of 50 patients, 44% had Thyroiditis, 26% had colloid goiter, 14% had mng, 8% had adenomatous nodule, 6% had mng with thyroiditis and 2% had medullary carcinoma. Conclusion: The presence of hypoechoic nodules, taller than wider with puntate calcification and presence of vascularity is highly specificity for malignant thyroid lesion.

Keywords
INTRODUCTION

It is superficial gland, It is easily seen since they are so close to the skin's surface. Disorders of thyroid gland commonly presents as hypothyroidism, goiter and rarely as hyperthyroidism[1]. Thyroid diseases form the major part amongst all the endocrine disorders, are suffering from one or the meajor thyroid disorders.

 

Thyroid gland is affected by various pathologies of which nodules are the most commonly encountered in clinical practice[2].

 

Thyroid nodules are palpable thyroid swelling in the gland, majority patient are asymptomatic. The prevalence of thyroid nodules/mass varies with age, affecting most of population older than 45 years age. Thyroid nodules are mostly found in females than in males, Thyroid lesions seen in countries where iodine intake is low[3].

 

Thyroid nodules are growth of within normal thyroid parenchyma with structural and/or functional changes seen, Thyroid nodules found sometimes incidentally and there is a no any symptoms can be simple nodule if there are absence of thyroid related disorder such as autoimmune disorder, malignancy up to 50 -60 % of patients have a solitary thyroid nodule are seen to have multiple thyroid nodules in ultrasound (US) [4].

 

Thyroid nodules are mainly seen in adults, prevalence rate of 40 -45% in individuals above aged 60 and above. Among the nodules, only a small amount is cancerous (9-15%), amoung the carcinoma papillary carcinoma is the most commonly seen in histopathology. Although most of predominanant are benign, a small amount of these nodules having malignant potential, thus underscoring the diagnostic precise. Thus, for ensuring the accurate diagnosis of thyroid nodes is crucial to avoid unnecessary surgical treatment and able timely early treatment in cases of the malignancy[5-6].

MATERIALS AND METHODS

The source of data is patients referred to the Department of Radio diagnosis, Amaltas Institute of Medical Sciences, Dewas, M.P. for ultrasonography in thyroid lesions. Patients having thyroid lesions in USG examination were studied. This study consists of approx 50 patients with thyroid lesions detected.

 

Ultrasonography was performed in a room with dim light. Sonography of neck will be done in all cases with 3-12 MHz (Mega Hertz) high frequency transducer probe. Patients was lying  in a supine position & neck slightly extended  backward. Neck ultrasound scan in grey scale was performed with patient of thyroid disorder of age group more than 18 year of age. Patients having findings of thyroid disorders by ultrasonography was to pathology department for FNAC fine needle aspiration cytology correlation.

 

Inclusion Criteria

  • Patients who are referred to the department for routine checkup of the neck were included.
  • Age group more than 18 years
  • Patient who are giving consent .

 

Exclusion Criteria

  • Patient who having bleeding disorder
  • Patient refused for fine needle aspiration cytology
  • Patient not giving consent.
  • Congenital thyroid disease
RESULTS

Table 1: Age group Distribution

Age Group

Frequency[f]

Percent

≤ 20

3

6.00

21-30

10

20.00

31-40

12

24.00

41-50

15

30.00

51-60

8

16.00

>60

2

4.00

Total

50

100.00

 

Table 2: ULTRASOUND DIAGNOSIS

ULTRASOUND DIAGNOSIS

Frequency

Percent

THYROIDITIS

22

44.00

COLLOID GOITER

13

26.00

MNG

7

14.00

ADENOMATOUS NODULE

4

8.00

MNG WITH THYROIDITIS

3

6.00

MEDULLARY CARCINOMA

1

2.00

Total

50

100.00

 

Table 3: SIZE OF THYROID GLAND

SIZE OF THYROID GLAND

Frequency

Percent

Normal.

13

26.00

Enlarged.

37

74.00

Total

50

100.00

 

Table 4: ECHOTEXTURE OF THYROID PARENCHYMA

ECHOTEXTURE OF THYROID PARENCHYMA

Frequency

Percent

Homogeneous

22

44.00

Heterogeenous

28

56.00

Total

50

100.00

 

Table 5: FNAC REPORT

FNAC REPORT

Frequency

Percent

COLLOID GOITER

15

30.00

FOLLICULAR NEOPLASM

3

6.00

MEDULLARY CARCINOMA

1

2.00

MNG

5

10.00

PAPILLARY CARCINOMA

1

2.00

THYROIDITIS

25

50.00

Total

50

100.00

 

DISCUSSION

In the these study, overall mean age are 40.30 ± 12.59 yrs .Narayanakar RP et all.[7], Srinivas MNS et al. [8], Studies also had supportive findings with the present study findings whereas Popli et al. [9] Study was contradict to our study findings. Most common age group was 41-50 years whereas >60 years was least common observed during the study. According to Bhise SV et al. [10] Study, 31-40 years of age group was more common observed during his findings.

 

In the present study, 30% had colloid goiter, 6% had follicular neoplasm, 2% had medullary carcinoma, 10% had MNG, 2% had Paplillary carcinoma and 50% had thyrodiits. According to Rathod GB et al. Study, 17% had colloid cyst, 30% had multinodular colloid goiter, 30% had colloid goiter, 6% had Chronic lymphocytic thyroiditis, 8% had follicular lesions, 4% had papillary carcinoma, 2% had anaplastic carcinoma and 3% had indeterminate lesions. Accoridng to Singh P. et al., 65.71% had colloid nodule, 17.14% had colloid goiter with cystic change, 1.43% had lymphocytic thyroiditis, adenomatous goiter, 1.43% had follicular neoplasm, 12.86%  had malignant lesions which included papillary carcinoma (10%) and medullary carcinoma (2.9%).

In the present study, 34.09% had < 5mm of nodule size, 15.91% had 5 mm-1cm of nodule size and 50% had >1 cm of nodule size. According to singh P. et al[11]. Study, 41.43% had < 5mm of nodule size, 38.57% had 5 mm-1cm of nodule size and 20% had >1 cm of nodule size.

 

In the present study, 30% had colloid goiter, 6% had follicular neoplasm, 2% had medullary carcinoma, 10% had MNG, 2% had Paplillary carcinoma and 50% had thyrodiits.According to Rathod GB et al. Study, 17% had colloid cyst, 30% had multinodular colloid goiter, 30% had colloid goiter, 6% had Chronic lymphocytic thyroiditis, 8% had follicular lesions, 4% had papillary carcinoma, 2% had anaplastic carcinoma and 3% had indeterminate lesions. Accoridng to Singh P. et al., 65.71% had colloid nodule, 17.14% had colloid goiter with cystic change, 1.43% had lymphocytic thyroiditis, adenomatous goiter, 1.43% had follicular neoplasm, 12.86%  had malignant lesions which included papillary carcinoma (10%) and medullary carcinoma (2.9%).

CONCLUSION

The presence of hypoechoic nodules, taller than wider with puntate calcification and presence of vascularity is highly specificity for malignant thyroid lesion.

REFERENCES
  1. Battina PK, Angelin Raju AJ, Reddy MR. A prospective study of correlation of ultrasonogram (usg), fine needle aspiration cytology (fnac) with postoperative histopathology in diagnosis of thyroid lesions in rural south india. Int J Acad Med Pharm. 2022;4(4):43-6.
  2. Borra RP. A study on evaluation of correlation between fnac and ultrasonography of neck in patients with thyroid lesions. International Journal of Medicine and Public Health, Vol 14, Issue 3, July- September, 2024.
  3. Nikita Mantri, Rishika Saraf, P. S. Mishrikotkar & D. B. Dahiphale. Correlation of Ultrasonography and Fine Needle Aspiration Cytology in Evaluation of Thyroid Nodules At Tertiary Care Centre. International Journal of Current Medical and Applied sciences; 2021,32(3), 36--43.
  4. Kumar EP, Namratha S, Pakanati SSR, Pokala U.Correlation of ultrasonography and fine needle aspiration cytology for diagnosis of malignancy in thyroid lesions: a study of 100 cases. Int J Otorhinolaryngol Head Neck Surg2021;7:1227-30.
  5. Alshaikh R, Almaghribi K, Alshammari DM, Mohamad H, Ebrahim W, Alshammari SM, Sabra O. Correlation between ultrasound and cytological findings of patients with suspicious thyroid nodules: the king Hamad University Hospital experience. Cureus. 2022 Mar;14(3).
  6. Osseis M, Jammal G, Kazan D, Noun R. Comparison between fine needle aspiration cytology with histopathology in the diagnosis of thyroid nodules. Journal of Personalized Medicine. 2023 Jul 28;13(8):1197.
  7. Narayanakar RP, Shetty DSG.A study of correlation of pre-operative fine needle aspiration cytology and ultrasonography with post-operative histopathology in thyroid swellings.Int Surg J2020;7:1456-60.
  8. Srinivas MN, Amogh VN, Gautam MS, Prathyusha IS, Vikram NR, Retnam MK, Balakrishna BV, Kudva N. A prospective study to evaluate the reliability of thyroid imaging reporting and data system in differentiation between benign and malignant thyroid lesions. Journal of Clinical Imaging Science. 2016 Feb 26;6:5.
  9. Popli MB, Rastogi A, Bhalla P, Solanki Y. Utility of gray-scale ultrasound to differentiate benign from malignant thyroid nodules. Indian J Radiol Imaging. 2012 Jan; 22(1):63–8.
  10. Bhise SV, Shaikh A, Hippargekar PM, Kothule S. A Prospective Study of Ultrasonographic and FNAC Correlation of Thyroid Swellings with Histopathology. Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1942-1948.
  11. Singh P, Gupta N, Dass A, Handa U, Singhal S: Correlation of fine needle aspiration cytology with histopathology in patients undergoing thyroid surgery. Otolaryngol Pol 2021; 75(4): 33-39.
Recommended Articles
Research Article
Morphometric Study of Adult Cadaveric Kidney
Published: 04/08/2025
Download PDF
Read Article
Research Article
To Study Clinical and Biochemical Profile and its Correlation with Hepatitis B Virus DNA Titre Among Hepatitis B Positive Patients in Disease Severity
...
Published: 31/07/2025
Download PDF
Read Article
Research Article
Anatomical Variations and Clinical Implications of the Upper Limb Nerves
Published: 28/02/2025
Download PDF
Read Article
Research Article
Study of Sleep Disorders in Patients Attending Psychiatry OPD at Tertiary Care Teaching Hospital of Western Uttar Pradesh
Published: 07/11/2019
Download PDF
Read Article
© Copyright Journal of Heart Valve Disease